Senpai

Why is this important to MADCast?
Its important to MADCast because people started calling Matt and Noah Senpai so much, that they changed their usernames to MrRedSenpai, and SenpaiTheorem for a week!

Meaning
It originates from anime and manga. It's someone older than you. Someone you look up to. If they give the slightest attention to you, you sort of explode. They are just really admired by you.